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» Mining Metabolic Networks for Optimal Drug Targets
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PSB
2008
15 years 2 months ago
Mining Metabolic Networks for Optimal Drug Targets
Padmavati Sridhar, Bin Song, Tamer Kahveci, Sanjay...
120
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BMCBI
2010
133views more  BMCBI 2010»
15 years 1 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
55
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PSB
2007
15 years 2 months ago
An Iterative Algorithm for Metabolic Network-Based Drug Target Identification
Padmavati Sridhar, Tamer Kahveci, Sanjay Ranka
BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
15 years 3 months ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
120
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CORR
2006
Springer
118views Education» more  CORR 2006»
15 years 1 months ago
Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge s
The organization and mining of malaria genomic and post-genomic data is important to significantly increase the knowledge of the biology of its causative agents, and is motivated,...
L.-M. Birkholtz, Olivier Bastien, G. Wells, D. Gra...