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BMCBI
2008
105views more  BMCBI 2008»
14 years 9 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
106
Voted
BMCBI
2008
159views more  BMCBI 2008»
14 years 9 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
CSCW
2008
ACM
14 years 9 months ago
Context-linked virtual assistants for distributed teams: an astrophysics case study
There is a growing need for distributed teams to analyze complex and dynamic data streams and make critical decisions under time pressure. Via a case study, we discuss potential g...
Sarah S. Poon, Rollin C. Thomas, Cecilia R. Aragon...
ALMOB
2006
155views more  ALMOB 2006»
14 years 9 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
81
Voted
ENVSOFT
2008
175views more  ENVSOFT 2008»
14 years 9 months ago
Automated regression-based statistical downscaling tool
Many impact studies require climate change information at a finer resolution than that provided by Global Climate Models (GCMs). In the last 10 years, downscaling techniques, both...
Masoud Hessami, Philippe Gachon, Taha B. M. J. Oua...
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