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» Model Based Analysis of Signaling Pathways
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JAMIA
2011
94views more  JAMIA 2011»
14 years 27 days ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...
BC
2004
114views more  BC 2004»
14 years 10 months ago
Spike timing and synaptic plasticity in the premotor pathway of birdsong
Abstract. The neural circuits of birdsong appear to utilize specific time delays in their operation. In particular, the anterior forebrain pathway (AFP) is implicated in an approxi...
Henry D. I. Abarbanel, Leif Gibb, Gabriel B. Mindl...
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Meta Analysis of Microarray Data Using Gene Regulation Pathways
Using microarray technology for genetic analysis in biological experiments requires computationally intensive tools to interpret results. The main objective here is to develop a â...
Saira Ali Kazmi, Yoo-Ah Kim, Baikang Pei, Ravi Nor...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
ISBI
2008
IEEE
15 years 4 months ago
Unsupervised segmentation of cell nuclei using geometric models
Fluorescent microscopy of biological samples allows noninvasive screening of specific molecular events in-situ. This approach is useful for investigating intricate signalling path...
Shaun Fitch, Trevor Jackson, Peter Andras, Craig R...