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116
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BMCBI
2004
111views more  BMCBI 2004»
15 years 2 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
132
Voted
BMCBI
2004
101views more  BMCBI 2004»
15 years 2 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
127
Voted
BMCBI
2004
128views more  BMCBI 2004»
15 years 2 months ago
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in struc
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
133
Voted
BMCBI
2004
91views more  BMCBI 2004»
15 years 2 months ago
SIGI: score-based identification of genomic islands
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Rainer Merkl
108
Voted
CCR
2004
143views more  CCR 2004»
15 years 2 months ago
The cutting EDGE of IP router configuration
Abstract-- Human error in configuring routers undermines attempts to provide reliable, predictable end-to-end performance on IP networks. Manual configuration, while expensive and ...
Donald F. Caldwell, Anna Gilbert, Joel Gottlieb, A...
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