19985 search results - page 3778 / 3997 » Modelling Ecological Data |
106
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
140
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
136
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
164
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
179
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...