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» Modelling Gene Regulatory Networks
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TON
2010
105views more  TON 2010»
14 years 4 months ago
Internet QoS and Regulations
This paper investigates the effects of transition from a single-service class to two-service classes in the Internet. We consider multiple competing Internet Service Providers (ISP...
Nikhil Shetty, Galina Schwartz, Jean C. Walrand
BMCBI
2006
75views more  BMCBI 2006»
14 years 10 months ago
A machine learning strategy to identify candidate binding sites in human protein-coding sequence
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
Thomas Down, Bernard Leong, Tim J. P. Hubbard
BMCBI
2010
167views more  BMCBI 2010»
14 years 10 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
14 years 12 months ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
AAAI
2008
15 years 5 days ago
Generating Application-Specific Benchmark Models for Complex Systems
Automated generators for synthetic models and data can play a crucial role in designing new algorithms/modelframeworks, given the sparsity of benchmark models for empirical analys...
Jun Wang, Gregory M. Provan