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» Modelling Gene Regulatory Networks
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HISB
2011
99views more  HISB 2011»
13 years 9 months ago
Quantitative Modeling the Saccharomyces cerevisiae FLR1 Regulatory Network Using an S-System Formalism
—We address the problem of finding a mathematical model for the genetic network regulating the stress response of the yeast Saccharomyces cerevisiae to the fungicide mancozeb. A...
Dulce Calçada, Susana Vinga, Ana T. Freitas...
GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
15 years 3 months ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
BIOWIRE
2007
Springer
15 years 4 months ago
Evolutionary and Temporal Dynamics of Transcriptional Regulatory Networks
Transcriptional regulation is a key mechanism that allows cells to make the appropriate amount of proteins at the right time. This is mediated by transcription factors that respond...
M. Madan Babu
BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
EUROGP
2006
Springer
140views Optimization» more  EUROGP 2006»
15 years 1 months ago
Evolving Noisy Oscillatory Dynamics in Genetic Regulatory Networks
We introduce a genetic programming (GP) approach for evolving genetic networks that demonstrate desired dynamics when simulated as a discrete stochastic process. Our representation...
André Leier, P. Dwight Kuo, Wolfgang Banzha...