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» Modelling Gene Regulatory Networks
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BMCBI
2010
183views more  BMCBI 2010»
14 years 7 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2005
102views more  BMCBI 2005»
14 years 9 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
ICDM
2003
IEEE
111views Data Mining» more  ICDM 2003»
15 years 3 months ago
OP-Cluster: Clustering by Tendency in High Dimensional Space
Clustering is the process of grouping a set of objects into classes of similar objects. Because of unknownness of the hidden patterns in the data sets, the definition of similari...
Jinze Liu, Wei Wang 0010
CMSB
2010
Springer
14 years 5 months ago
Action-based analysis of discrete regulatory networks with short-term stimuli
To incorporate instant effects and different timescales within a single biological system, an extension of discrete regulatory networks with short-term stimuli is proposed. By mai...
Christian Krause, Carola Krause, Erik P. de Vink
CIBB
2008
14 years 12 months ago
Curating a Large-Scale Regulatory Network by Evaluating Its Consistency with Expression Datasets
Abstract. The analysis of large-scale regulatory models using data issued from genome-scale high-throughput experimental techniques is an actual challenge in the systems biology fi...
Carito Guziolowski, Jeremy Gruel, Ovidiu Radulescu...