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» Modelling Gene Regulatory Networks
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SIAMSC
2008
149views more  SIAMSC 2008»
14 years 10 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
BMCBI
2007
127views more  BMCBI 2007»
14 years 10 months ago
Characterization and simulation of cDNA microarray spots using a novel mathematical model
Background: The quality of cDNA microarray data is crucial for expanding its application to other research areas, such as the study of gene regulatory networks. Despite the fact t...
Hye Young Kim, Seo Eun Lee, Min Jung Kim, Jin Il H...
CMSB
2004
Springer
15 years 1 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...
BMCBI
2006
169views more  BMCBI 2006»
14 years 10 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
TSP
2008
132views more  TSP 2008»
14 years 10 months ago
Robust Intervention in Probabilistic Boolean Networks
Probabilistic Boolean networks (PBNs) have been recently introduced as a paradigm for modeling genetic regulatory networks. One of the objectives of PBN modeling is to use the netw...
Ranadip Pal, Aniruddha Datta, Edward R. Dougherty