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» Models and Methods in Comparative Genomics
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BMCBI
2007
115views more  BMCBI 2007»
14 years 10 months ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
ALMOB
2006
135views more  ALMOB 2006»
14 years 10 months ago
P-value based visualization of codon usage data
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
CSDA
2008
128views more  CSDA 2008»
14 years 10 months ago
Assessing agreement of clustering methods with gene expression microarray data
In the rapidly evolving field of genomics, many clustering and classification methods have been developed and employed to explore patterns in gene expression data. Biologists face...
Xueli Liu, Sheng-Chien Lee, George Casella, Gary F...
JCB
2007
94views more  JCB 2007»
14 years 9 months ago
A Quantile Method for Sizing Optical Maps
Optical mapping is an integrated system for the analysis of single DNA molecules. It constructs restriction maps (noted as “optical map”) from individual DNA molecules present...
Haifeng Li, Anton Valouev, David C. Schwartz, Mich...
BMCBI
2002
188views more  BMCBI 2002»
14 years 9 months ago
The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
Background: The biomedical community is developing new methods of data analysis to more efficiently process the massive data sets produced by microarray experiments. Systematic an...
David M. Mutch, Alvin Berger, Robert Mansourian, A...