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» Multi-functional Protein Clustering in PPI Networks
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NAR
2011
225views Computer Vision» more  NAR 2011»
13 years 21 days ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
13 years 7 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
BMCBI
2010
120views more  BMCBI 2010»
13 years 10 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...
BIRD
2008
Springer
163views Bioinformatics» more  BIRD 2008»
13 years 12 months ago
Multi-functional Protein Clustering in PPI Networks
Abstract. Protein-Protein Interaction (PPI) networks contain valuable information for the isolation of groups of proteins that participate in the same biological function. Many pro...
Clara Pizzuti, Simona E. Rombo
IJDMB
2007
114views more  IJDMB 2007»
13 years 9 months ago
A parallel edge-betweenness clustering tool for Protein-Protein Interaction networks
: The increasing availability of protein-protein interaction graphs (PPI) requires new efficient tools capable of extracting valuable biological knowledge from these networks. Amon...
Qiaofeng Yang, Stefano Lonardi