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BMCBI
2007
141views more  BMCBI 2007»
14 years 12 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
BMCBI
2010
94views more  BMCBI 2010»
14 years 12 months ago
Comparison study of microarray meta-analysis methods
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
Anna Campain, Yee Hwa Yang
BMCBI
2010
87views more  BMCBI 2010»
14 years 12 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2007
117views more  BMCBI 2007»
14 years 12 months ago
Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
Xinan Yang, Xiao Sun
BMCBI
2007
109views more  BMCBI 2007»
14 years 12 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...