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BMCBI
2006
150views more  BMCBI 2006»
15 years 3 months ago
Instance-based concept learning from multiclass DNA microarray data
Background: Various statistical and machine learning methods have been successfully applied to the classification of DNA microarray data. Simple instance-based classifiers such as...
Daniel P. Berrar, Ian Bradbury, Werner Dubitzky
BMCBI
2006
129views more  BMCBI 2006»
15 years 3 months ago
BIPAD: A web server for modeling bipartite sequence elements
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Chengpeng Bi, Peter K. Rogan
BMCBI
2006
138views more  BMCBI 2006»
15 years 3 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
INTEGRATOR: interactive graphical search of large protein interactomes over the Web
Background: The rapid growth of protein interactome data has elevated the necessity and importance of network analysis tools. However, unlike pure text data, network search spaces...
Aaron N. Chang, Jason McDermott, Zachary Frazier, ...
BMCBI
2006
122views more  BMCBI 2006»
15 years 3 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
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