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» Multiple Sequence Alignment Based on Profile Alignment of In...
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114
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NAR
2000
123views more  NAR 2000»
15 years 3 months ago
Update of AMmtDB: a database of multi-aligned Metazoa mitochondrial DNA sequences
The AMmtDB database (http://bio-www.ba.cnr.it:8000/ srs6/ ) has been updated by collecting the multi-aligned sequences of Chordata mitochondrial genes coding for proteins and tRNA...
Cecilia Lanave, Sabino Liuni, Flavio Licciulli, Ma...
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
15 years 3 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
ALMOB
2006
155views more  ALMOB 2006»
15 years 3 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
191
Voted
BMCBI
2011
14 years 7 months ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes
IPPS
2006
IEEE
15 years 9 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan