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» Multiple Sequence Alignment Based on Profile Alignment of In...
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NAR
2000
123views more  NAR 2000»
14 years 11 months ago
Update of AMmtDB: a database of multi-aligned Metazoa mitochondrial DNA sequences
The AMmtDB database (http://bio-www.ba.cnr.it:8000/ srs6/ ) has been updated by collecting the multi-aligned sequences of Chordata mitochondrial genes coding for proteins and tRNA...
Cecilia Lanave, Sabino Liuni, Flavio Licciulli, Ma...
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
14 years 11 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
ALMOB
2006
155views more  ALMOB 2006»
14 years 11 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
BMCBI
2011
14 years 3 months ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes
IPPS
2006
IEEE
15 years 5 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan