Nonlinear random effects models with finite mixture structures are used to identify polymorphism in pharmacokinetic/ pharmacodynamic (PK/PD) phenotypes. An EM algorithm for maxim...
Xiaoning Wang, Alan Schumitzky, David Z. D'Argenio
The ability to integrate diverse components such as processor cores, memories, custom hardware blocks and complex network-on-chip (NoC) communication frameworks onto a single chip...
Jason Cong, Karthik Gururaj, Guoling Han, Adam Kap...
Data-intensive applications that operate on large volumes of data have motivated a fresh look at the design of data center networks. The first wave of proposals focused on designi...
Guohui Wang, David G. Andersen, Michael Kaminsky, ...
We address performance issues associated with simulationbased algorithms for optimizing Markov reward processes. Specifically, we are concerned with algorithms that exploit the re...
An increase in the performance of deteriorating systems can be achieved through the adoption of suitable maintenance policies. One of the most popular maintenance policies is the ...