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» Network constrained clustering for gene microarray data
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BMCBI
2010
124views more  BMCBI 2010»
14 years 9 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
SDM
2009
SIAM
251views Data Mining» more  SDM 2009»
15 years 6 months ago
High Performance Parallel/Distributed Biclustering Using Barycenter Heuristic.
Biclustering refers to simultaneous clustering of objects and their features. Use of biclustering is gaining momentum in areas such as text mining, gene expression analysis and co...
Alok N. Choudhary, Arifa Nisar, Waseem Ahmad, Wei-...
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
ALMOB
2006
109views more  ALMOB 2006»
14 years 9 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
15 years 1 months ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert