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BMCBI
2008
82views more  BMCBI 2008»
14 years 9 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey
BMCBI
2010
129views more  BMCBI 2010»
14 years 9 months ago
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks
Background: Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological fu...
Lina Chen, Hong Wang, Liangcai Zhang, Wan Li, Qian...
BMCBI
2008
118views more  BMCBI 2008»
14 years 9 months ago
Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
Rekin's Janky, Jacques van Helden
BMCBI
2007
156views more  BMCBI 2007»
14 years 9 months ago
Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
BMCBI
2008
153views more  BMCBI 2008»
14 years 9 months ago
Version VI of the ESTree db: an improved tool for peach transcriptome analysis
Background: The ESTree database (db) is a collection of Prunus persica and Prunus dulcis EST sequences that in its current version encompasses 75,404 sequences from 3 almond and 1...
Barbara Lazzari, Andrea Caprera, Alberto Vecchiett...