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» On Probabilistic Alternating Simulations
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BMCBI
2008
149views more  BMCBI 2008»
14 years 10 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
CN
2010
152views more  CN 2010»
14 years 10 months ago
An environment-aware mobility model for wireless ad hoc network
Simulation is a cost effective, fast and flexible alternative to test-beds or practical deployment for evaluating the characteristics and potential of mobile ad hoc networks. Sinc...
Sabbir Ahmed, Gour C. Karmakar, Joarder Kamruzzama...
BMCBI
2006
101views more  BMCBI 2006»
14 years 10 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
BMCBI
2006
165views more  BMCBI 2006»
14 years 10 months ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
BMCBI
2006
153views more  BMCBI 2006»
14 years 10 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...