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BMCBI
2008
114views more  BMCBI 2008»
14 years 10 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
CORR
2010
Springer
116views Education» more  CORR 2010»
14 years 10 months ago
Where are the hard manipulation problems?
One possible escape from the Gibbard-Satterthwaite theorem is computational complexity. For example, it is NP-hard to compute if the STV rule can be manipulated. However, there is...
Toby Walsh
BMCBI
2006
195views more  BMCBI 2006»
14 years 9 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona
BMCBI
2006
151views more  BMCBI 2006»
14 years 9 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2007
102views more  BMCBI 2007»
14 years 9 months ago
Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
Luis A. Diago, Persy Morell, Longendri Aguilera, E...