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» On Suboptimal Alignments of Biological Sequences
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BMCBI
2008
138views more  BMCBI 2008»
14 years 12 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2008
144views more  BMCBI 2008»
14 years 12 months ago
Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
Background: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such as alignments comprising te...
Olivo Miotto, Tin Wee Tan, Vladimir Brusic
ALMOB
2006
89views more  ALMOB 2006»
14 years 12 months ago
On the maximal cliques in c-max-tolerance graphs and their application in clustering molecular sequences
Given a set S of n locally aligned sequences, it is a needed prerequisite to partition it into groups of very similar sequences to facilitate subsequent computations, such as the ...
Katharina Anna Lehmann, Michael Kaufmann, Stephan ...
RECOMB
2004
Springer
16 years 3 days ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
ISMB
1998
15 years 1 months ago
Bayesian Protein Family Classifier
A Bayesian procedure for the simultaneous alignment and classification of sequences into subclasses is described. This Gibbs sampling algorithm iterates between an alignment step ...
Kunbin Qu, Lee Ann McCue, Charles E. Lawrence