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» On the Average-Case Complexity of Property Testing
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BMCBI
2007
126views more  BMCBI 2007»
13 years 6 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2008
78views more  BMCBI 2008»
13 years 6 months ago
Deducing topology of protein-protein interaction networks from experimentally measured sub-networks
Background: Protein-protein interaction networks are commonly sampled using yeast two hybrid approaches. However, whether topological information reaped from these experimentallym...
Ling Yang, Thomas M. Vondriska, Zhangang Han, W. R...
FOCM
2008
100views more  FOCM 2008»
13 years 6 months ago
A Unifying Local Convergence Result for Newton's Method in Riemannian Manifolds
We consider the problem of finding a singularity of a differentiable vector field X defined on a complete Riemannian manifold. We prove a unified result for the existence and local...
Felipe Alvarez, Jérôme Bolte, Julien ...
BMCBI
2006
101views more  BMCBI 2006»
13 years 6 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
BMCBI
2007
215views more  BMCBI 2007»
13 years 6 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer