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BMCBI
2008
170views more  BMCBI 2008»
15 years 1 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
BMCBI
2006
119views more  BMCBI 2006»
15 years 1 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2006
100views more  BMCBI 2006»
15 years 1 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
ISCI
2008
165views more  ISCI 2008»
15 years 1 months ago
Support vector regression from simulation data and few experimental samples
This paper considers nonlinear modeling based on a limited amount of experimental data and a simulator built from prior knowledge. The problem of how to best incorporate the data ...
Gérard Bloch, Fabien Lauer, Guillaume Colin...
JACM
2006
93views more  JACM 2006»
15 years 1 months ago
Combining expert advice in reactive environments
"Experts algorithms" constitute a methodology for choosing actions repeatedly, when the rewards depend both on the choice of action and on the unknown current state of t...
Daniela Pucci de Farias, Nimrod Megiddo
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