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BMCBI
2006
158views more  BMCBI 2006»
14 years 9 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
BMCBI
2006
100views more  BMCBI 2006»
14 years 9 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
CN
2006
61views more  CN 2006»
14 years 9 months ago
Structuring topologically aware overlay networks using domain names
Abstract-- Overlay networks are application layer systems which facilitate users in performing distributed functions such as searches over the contents of other users. An important...
Demetrios Zeinalipour-Yazti, Vana Kalogeraki
CONSTRAINTS
2006
77views more  CONSTRAINTS 2006»
14 years 9 months ago
The Impact of Search Heuristics on Heavy-Tailed Behaviour
Abstract. The heavy-tailed phenomenon that characterises the runtime distributions of backtrack search procedures has received considerable attention over the past few years. Some ...
Tudor Hulubei, Barry O'Sullivan
BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj