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BMCBI
2008
98views more  BMCBI 2008»
15 years 25 days ago
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
Background: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aber...
Johan Staaf, Johan Vallon-Christersson, David Lind...
ALMOB
2006
155views more  ALMOB 2006»
15 years 24 days ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
ENVSOFT
2008
175views more  ENVSOFT 2008»
15 years 24 days ago
Automated regression-based statistical downscaling tool
Many impact studies require climate change information at a finer resolution than that provided by Global Climate Models (GCMs). In the last 10 years, downscaling techniques, both...
Masoud Hessami, Philippe Gachon, Taha B. M. J. Oua...
BMCBI
2006
184views more  BMCBI 2006»
15 years 24 days ago
PathSys: integrating molecular interaction graphs for systems biology
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...
Michael Baitaluk, Xufei Qian, Shubhada Godbole, Al...
112
Voted
BMCBI
2006
124views more  BMCBI 2006»
15 years 24 days ago
ZCURVE_V: a new self-training system for recognizing protein-coding genes in viral and phage genomes
Background: It necessary to use highly accurate and statistics-based systems for viral and phage genome annotations. The GeneMark systems for gene-finding in virus and phage genom...
Feng-Biao Guo, Chun-Ting Zhang
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