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CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Maximum Sequence Alignment Fails to Predict Off-targeted Gene Regulation by RNAi
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
Amanda Birmingham, Emily M. Anderson, William S. M...
NAR
2011
202views Computer Vision» more  NAR 2011»
14 years 26 days ago
PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family
PREX (http://www.csb.wfu.edu/prex/) is a database of currently 3516 peroxiredoxin (Prx or PRDX) protein sequences unambiguously classified into one of six distinct subfamilies. Pe...
Laura Soito, Chris Williamson, Stacy T. Knutson, J...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
14 years 10 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
ESANN
2006
14 years 11 months ago
Visualizing gene interaction graphs with local multidimensional scaling
Several bioinformatics data sets are naturally represented as graphs, for instance gene regulation, metabolic pathways, and proteinprotein interactions. The graphs are often large ...
Jarkko Venna, Samuel Kaski
BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
14 years 7 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo