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CSB
2005
IEEE
180views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Functional Modularity in a Large-Scale Mammalian Molecular Interaction Network
The Ingenuity™ Pathways Knowledge Base (IPKB) contains over one million findings manually curated from the scientific literature. Highly-structured content from the IPKB forms...
Andreas Kramer, Daniel R. Richards, James O. Bowlb...
BMCBI
2006
112views more  BMCBI 2006»
14 years 10 months ago
Phylophenetic properties of metabolic pathway topologies as revealed by global analysis
Background: As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components. In the post-genomic e...
Yong Zhang, Shaojuan Li, Geir Skogerbø, Zhi...
BIBM
2008
IEEE
111views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Estimating Regulatory Associations of Genomic Loci and Biological Pathways in Lymphoblastoid Cells
Genetical genomics has been established to study genetic variation of gene expression. It treats transcript expression as a quantitative trait and identifies putative regulatory l...
Jung Hoon Woo, Eunjee Lee, Sung-Bum Cho, Ju Han Ki...
ICTAI
2003
IEEE
15 years 3 months ago
Adaptive Modeling of Biochemical Pathways
In bioinformatics, biochemical pathways can be modeled by many differential equations. It is still an open problem how to fit the huge amount of parameters of the equations to the...
Rüdiger W. Brause
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Meta Analysis of Microarray Data Using Gene Regulation Pathways
Using microarray technology for genetic analysis in biological experiments requires computationally intensive tools to interpret results. The main objective here is to develop a ...
Saira Ali Kazmi, Yoo-Ah Kim, Baikang Pei, Ravi Nor...