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BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
ESLpred2: improved method for predicting subcellular localization of eukaryotic proteins
Background: The expansion of raw protein sequence databases in the post genomic era and availability of fresh annotated sequences for major localizations particularly motivated us...
Aarti Garg, Gajendra P. S. Raghava
TSP
2008
114views more  TSP 2008»
14 years 10 months ago
Universal Switching Linear Least Squares Prediction
We consider sequential regression of individual sequences under the square error loss. Using a competitive algorithm framework, we construct a sequential algorithm that can achieve...
Suleyman Serdar Kozat, Andrew C. Singer
BMCBI
2005
117views more  BMCBI 2005»
14 years 10 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
BMCBI
2007
143views more  BMCBI 2007»
14 years 10 months ago
RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules
Background: In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular ...
Yair Horesh, Tirza Doniger, Shulamit Michaeli, Ron...
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BMCBI
2010
105views more  BMCBI 2010»
14 years 10 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang