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» Practical Differential Profiling
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BMCBI
2010
142views more  BMCBI 2010»
14 years 7 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
CSCW
2012
ACM
13 years 5 months ago
Boundary regulation in social media
The management of group context in socially mediating technologies is an important challenge for the design community. To better understand how users manage group context, we expl...
Stutzman Frederic, Hartzog Woodrow
90
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SEMWEB
2009
Springer
15 years 4 months ago
Towards a Graphical Notation for OWL 2
The Ontology Definition Metamodel (ODM) defines a set of UML metamodels and profiles for development of RDF and OWL. The UML profiles in the ODM specification adapt UML notations t...
Elisa F. Kendall, Roy Bell, Roger Burkhart, Mark D...
CGO
2003
IEEE
15 years 1 months ago
Optimal and Efficient Speculation-Based Partial Redundancy Elimination
Existing profile-guided partial redundancy elimination (PRE) methods use speculation to enable the removal of partial redundancies along more frequently executed paths at the expe...
Qiong Cai, Jingling Xue
BMCBI
2011
14 years 4 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman