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BMCBI
2011
14 years 4 months ago
PRIN, a predicted rice interactome network
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
Haibin Gu, Pengcheng Zhu, Yinming Jiao, Yijun Meng...
BMCBI
2010
132views more  BMCBI 2010»
15 years 1 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
BMCBI
2010
82views more  BMCBI 2010»
15 years 1 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...
BMCBI
2008
104views more  BMCBI 2008»
15 years 1 months ago
InteroPORC: an automated tool to predict highly conserved protein interaction networks
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
Magali Michaut, Samuel Kerrien, Luisa Montecchi-Pa...
NSDI
2008
15 years 3 months ago
Predicted and Observed User Behavior in the Weakest-link Security Game
We aim to advance the understanding of individual security decision-making, by combining formal and behavioral analysis. We sketch a game-theoretic model of security decision-maki...
Jens Grossklags, Nicolas Christin, John Chuang