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» Predicting protein function from domain content
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ALMOB
2006
155views more  ALMOB 2006»
15 years 5 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
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BMCBI
2006
85views more  BMCBI 2006»
15 years 5 months ago
On single and multiple models of protein families for the detection of remote sequence relationships
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
James A. Casbon, Mansoor A. S. Saqi
BMCBI
2007
151views more  BMCBI 2007»
15 years 5 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
BMCBI
2007
114views more  BMCBI 2007»
15 years 5 months ago
Probabilistic prediction and ranking of human protein-protein interactions
Background: Although the prediction of protein-protein interactions has been extensively investigated for yeast, few such datasets exist for the far larger proteome in human. Furt...
Michelle S. Scott, Geoffrey J. Barton
IJBRA
2007
80views more  IJBRA 2007»
15 years 5 months ago
On predicting secondary structure transition
A function of a protein is dependent on its structure; therefore, predicting a protein structure from an amino acid sequence is an active area of research. Optimally predicting a ...
Raja Loganantharaj, Vivek Philip