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BMCBI
2010
81views more  BMCBI 2010»
13 years 5 months ago
Empirical Bayes Analysis of Sequencing-based Transcriptional Profiling without Replicates
Background: Recent technological advancements have made high throughput sequencing an increasingly popular approach for transcriptome analysis. Advantages of sequencing-based tran...
Zhijin Wu, Bethany D. Jenkins, Tatiana A. Rynearso...
BMCBI
2011
13 years 23 days ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
BMCBI
2010
178views more  BMCBI 2010»
13 years 6 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2006
139views more  BMCBI 2006»
13 years 6 months ago
Integrated functional visualization of eukaryotic genomes
Background: Increasing amounts of data from large scale whole genome analysis efforts demands convenient tools for manipulation, visualization and investigation. Whole genome plot...
Rohit Ghai, Hannes Lindemann, Trinad Chakraborty
BMCBI
2010
240views more  BMCBI 2010»
13 years 6 months ago
TAM: A method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
Background: MicroRNAs (miRNAs) are a class of important gene regulators. The number of identified miRNAs has been increasing dramatically in recent years. An emerging major challe...
Ming Lu, Bing Shi, Juan Wang, Qun Cao, Qinghua Cui