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ALMOB
2006
138views more  ALMOB 2006»
14 years 9 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
AUTOMATICA
2006
125views more  AUTOMATICA 2006»
14 years 9 months ago
Optimization over state feedback policies for robust control with constraints
This paper is concerned with the optimal control of linear discrete-time systems, which are subject to unknown but bounded state disturbances and mixed constraints on the state an...
Paul J. Goulart, Eric C. Kerrigan, Jan M. Maciejow...
BMCBI
2006
134views more  BMCBI 2006»
14 years 9 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
DATAMINE
2006
127views more  DATAMINE 2006»
14 years 9 months ago
Computing LTS Regression for Large Data Sets
Least trimmed squares (LTS) regression is based on the subset of h cases (out of n) whose least squares t possesses the smallest sum of squared residuals. The coverage h may be se...
Peter Rousseeuw, Katrien van Driessen
BMCBI
2007
110views more  BMCBI 2007»
14 years 9 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...