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» Probabilistic Model Checking of Complex Biological Pathways
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IPL
2007
125views more  IPL 2007»
15 years 7 days ago
State explosion in almost-sure probabilistic reachability
We show that the problem of reaching a state set with probability 1 in probabilisticnondeterministic systems operating in parallel is EXPTIME-complete. We then show that this prob...
François Laroussinie, Jeremy Sproston
166
Voted
BMCBI
2005
169views more  BMCBI 2005»
15 years 7 days ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
113
Voted
DILS
2009
Springer
15 years 4 months ago
An Integration and Analysis Pipeline for Systems Biology in Crop Plant Metabolism
Abstract. To advance the comprehension of complex biological processes occurring in crop plants (e.g. for improvement of growth or yield) it is of high interest to reconstruct and ...
Stephan Weise, Christian Colmsee, Eva Grafahrend-B...
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Meta Analysis of Microarray Data Using Gene Regulation Pathways
Using microarray technology for genetic analysis in biological experiments requires computationally intensive tools to interpret results. The main objective here is to develop a â...
Saira Ali Kazmi, Yoo-Ah Kim, Baikang Pei, Ravi Nor...
BMCBI
2010
150views more  BMCBI 2010»
15 years 14 days ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...