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ISBI
2007
IEEE
15 years 3 months ago
Shape Analysis Using Curvature-Based Descriptors and Profile Hidden Markov Models
This paper presents a new framework for shape modeling and analysis. A shape instance is described by a curvature-based shape descriptor. A Profile Hidden Markov Model (PHMM) is ...
Rui Huang, Vladimir Pavlovic, Dimitris N. Metaxas
BMCBI
2005
141views more  BMCBI 2005»
14 years 9 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
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BIOINFORMATICS
1998
69views more  BIOINFORMATICS 1998»
14 years 9 months ago
Profile hidden Markov models
Sean R. Eddy
IPPS
2007
IEEE
15 years 3 months ago
High Performance Database Searching with HMMer on FPGAs
1 Profile Hidden Markov Models (profile HMMs) are used as a popular bioinformatics tool for sensitive database searching, e.g. a set of not annotated protein sequences is compared...
Timothy F. Oliver, Leow Yuan Yeow, Bertil Schmidt