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ISBI
2007
IEEE
15 years 6 months ago
Shape Analysis Using Curvature-Based Descriptors and Profile Hidden Markov Models
This paper presents a new framework for shape modeling and analysis. A shape instance is described by a curvature-based shape descriptor. A Profile Hidden Markov Model (PHMM) is ...
Rui Huang, Vladimir Pavlovic, Dimitris N. Metaxas
BMCBI
2005
141views more  BMCBI 2005»
14 years 11 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
BIOINFORMATICS
1998
69views more  BIOINFORMATICS 1998»
14 years 11 months ago
Profile hidden Markov models
Sean R. Eddy
IPPS
2007
IEEE
15 years 6 months ago
High Performance Database Searching with HMMer on FPGAs
1 Profile Hidden Markov Models (profile HMMs) are used as a popular bioinformatics tool for sensitive database searching, e.g. a set of not annotated protein sequences is compared...
Timothy F. Oliver, Leow Yuan Yeow, Bertil Schmidt