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CHI
1993
ACM
15 years 1 months ago
Exploring the applications of user-expertise assessment for intelligent interfaces
An adaptive user interface relies, to a large extent, upon an adequate user model (e.g., a representationof user-expertise). However, building a user model may be a tedious and ti...
Michel Desmarais, Jiming Liu
BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
144views more  BMCBI 2008»
14 years 9 months ago
Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...
Yanxin Huang, Yongli Bao, Shu Yan Guo, Yan Wang, C...
94
Voted
BMCBI
2006
101views more  BMCBI 2006»
14 years 9 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...