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BMCBI
2008
122views more  BMCBI 2008»
13 years 6 months ago
Determining gene expression on a single pair of microarrays
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
Robert W. Reid, Anthony A. Fodor
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
13 years 12 months ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
BMCBI
2010
80views more  BMCBI 2010»
13 years 6 months ago
Power and sample size estimation in microarray studies
Background: Before conducting a microarray experiment, one important issue that needs to be determined is the number of arrays required in order to have adequate power to identify...
Wei-Jiun Lin, Huey-miin Hsueh, James J. Chen
BMCBI
2004
150views more  BMCBI 2004»
13 years 6 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
BMCBI
2008
167views more  BMCBI 2008»
13 years 6 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli