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» Retrieval of 3D protein structures
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SMI
2005
IEEE
15 years 3 months ago
Volumetric Data Analysis using Morse-Smale Complexes
The 3D Morse-Smale complex is a fundamental topological construct that partitions the domain of a real-valued function into regions having uniform gradient flow behavior. In this...
Vijay Natarajan, Valerio Pascucci
EVOW
2007
Springer
15 years 1 months ago
Classification of Cell Fates with Support Vector Machine Learning
In human mesenchymal stem cells the envelope surrounding the nucleus, as visualized by the nuclear lamina, has a round and flat shape. The lamina structure is considerably deformed...
Ofer M. Shir, Vered Raz, Roeland W. Dirks, Thomas ...
BMCBI
2006
84views more  BMCBI 2006»
14 years 9 months ago
Representation of target-bound drugs by computed conformers: implications for conformational libraries
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
Stefan Günther, Christian Senger, Elke Michal...
BMCBI
2010
163views more  BMCBI 2010»
14 years 9 months ago
Integration of open access literature into the RCSB Protein Data Bank using BioLit
Background: Biological data have traditionally been stored and made publicly available through a variety of on-line databases, whereas biological knowledge has traditionally been ...
Andreas Prlic, Marco A. Martinez, Dimitris Dimitro...
BMCBI
2008
106views more  BMCBI 2008»
14 years 9 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...