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BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
15 years 29 days ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
111
Voted
BMCBI
2010
101views more  BMCBI 2010»
15 years 29 days ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
99
Voted
BMCBI
2010
173views more  BMCBI 2010»
15 years 28 days ago
The Yeast Resource Center Public Image Repository: A large database of fluorescence microscopy images
Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subc...
Michael Riffle, Trisha N. Davis
117
Voted
BMCBI
2010
105views more  BMCBI 2010»
15 years 28 days ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
100
Voted
BMCBI
2010
148views more  BMCBI 2010»
15 years 28 days ago
Analysis of interactions between ribosomal proteins and RNA structural motifs
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
Giovanni Ciriello, Claudio Gallina, Concettina Gue...
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