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BMCBI
2010
97views more  BMCBI 2010»
15 years 26 days ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
BMCBI
2007
109views more  BMCBI 2007»
15 years 26 days ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
113
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BMCBI
2008
84views more  BMCBI 2008»
15 years 26 days ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
113
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BMCBI
2007
182views more  BMCBI 2007»
15 years 26 days ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...
150
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EC
2008
120views ECommerce» more  EC 2008»
15 years 25 days ago
Genetic Algorithms with Memory- and Elitism-Based Immigrants in Dynamic Environments
In recent years the genetic algorithm community has shown a growing interest in studying dynamic optimization problems. Several approaches have been devised. The random immigrants...
Shengxiang Yang