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BMCBI
2011
14 years 4 months ago
HomPPI: A Class of Sequence Homology Based Protein-Protein Interface Prediction Methods
Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Li C. Xue, Drena Dobbs, Vasant Honavar
ALMOB
2008
131views more  ALMOB 2008»
15 years 29 days ago
Fast algorithms for computing sequence distances by exhaustive substring composition
The increasing throughput of sequencing raises growing needs for methods of sequence analysis and comparison on a genomic scale, notably, in connection with phylogenetic tree reco...
Alberto Apostolico, Olgert Denas
BMCBI
2010
95views more  BMCBI 2010»
15 years 28 days ago
Quantifying the relationship between sequence and three-dimensional structure conservation in RNA
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
Emidio Capriotti, Marc A. Martí-Renom
116
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BMCBI
2010
129views more  BMCBI 2010»
15 years 28 days ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
99
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BMCBI
2005
84views more  BMCBI 2005»
15 years 22 days ago
Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
Youfang Cao, Lianjie Wang, Kexue Xu, Chunhai Kou, ...