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ALMOB
2006
155views more  ALMOB 2006»
15 years 1 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
ALMOB
2006
106views more  ALMOB 2006»
15 years 1 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
AMAI
2006
Springer
15 years 1 months ago
An algebraic framework for temporal attribute characteristics
Most real-world database applications manage temporal data, i.e., data with associated time references that capture a temporal aspect of the data, typically either when the data i...
Michael H. Böhlen, Johann Gamper, Christian S...
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
15 years 1 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2006
145views more  BMCBI 2006»
15 years 1 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
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