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BMCBI
2007
265views more  BMCBI 2007»
14 years 10 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
107
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ALMOB
2006
109views more  ALMOB 2006»
14 years 10 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
WWW
2007
ACM
15 years 11 months ago
BOWiki - a Collaborative Annotation and Ontology Curation Framework
As the amount of data being generated in biology has increased, a major challenge has been how to store and represent this data in a way that makes it easily accessible to researc...
Michael Backhaus, Janet Kelso, Joshua Bacher, Hein...
106
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BMCBI
2011
14 years 1 months ago
Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
Artem Lysenko, Michael Defoin-Platel, Keywan Hassa...
BMCBI
2011
14 years 5 months ago
Clinical Synopsis Search in OMIM
Background: The OMIM database is a tool used daily by geneticists. Syndrome pages include a Clinical Synopsis section containing a list of known phenotypes comprising a clinical s...
Raphael Cohen, Avitan Gefen, Michael Elhadad, Ohad...