Abstract. Biological systems involving genetic reactions are large discrete event systems, and often contain certain species that occur in small quantities, and others that occur i...
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
We apply the multi-agent system (MAS) platform to the task of biological network simulation. In this paper, we describe the simulation of signal transduction (ST) networks using t...
Salim Khan, Ravi Makkena, Foster McGeary, Keith S....
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...