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» Stochastic approaches for modelling in vivo reactions
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HYBRID
2004
Springer
13 years 11 months ago
Dynamic Partitioning of Large Discrete Event Biological Systems for Hybrid Simulation and Analysis
Abstract. Biological systems involving genetic reactions are large discrete event systems, and often contain certain species that occur in small quantities, and others that occur i...
Natasha A. Neogi
SIAMSC
2008
149views more  SIAMSC 2008»
13 years 6 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
ATAL
2003
Springer
13 years 11 months ago
A multi-agent system for the quantitative simulation of biological networks
We apply the multi-agent system (MAS) platform to the task of biological network simulation. In this paper, we describe the simulation of signal transduction (ST) networks using t...
Salim Khan, Ravi Makkena, Foster McGeary, Keith S....
HYBRID
2001
Springer
13 years 10 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 7 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...