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DAGSTUHL
2006
15 years 10 days ago
Modeling and Simulating Biological Processes with Stochastic Multiset Rewriting
ed Abstract Membrane systems are models of computation inspired by the structure and the function of biological cells. The model was introduced in 1998 by Gh. Paun and since then m...
Matteo Cavaliere, Sean Sedwards
GECCO
2009
Springer
15 years 5 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
BMCBI
2007
113views more  BMCBI 2007»
14 years 11 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...
ALMOB
2006
80views more  ALMOB 2006»
14 years 11 months ago
Pattern statistics on Markov chains and sensitivity to parameter estimation
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...
Grégory Nuel
EVOW
2008
Springer
15 years 22 days ago
Enhancing Parameter Estimation of Biochemical Networks by Exponentially Scaled Search Steps
A fundamental problem of modelling in Systems Biology is to precisely characterise quantitative parameters, which are hard to measure experimentally. For this reason, it is common ...
Hendrik Rohn, Bashar Ibrahim, Thorsten Lenser, Tho...