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» Structured Sparsity in Structured Prediction
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129
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BMCBI
2008
87views more  BMCBI 2008»
15 years 5 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2007
168views more  BMCBI 2007»
15 years 5 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
134
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 5 months ago
Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
Marcel Schmidt am Busch, Anne Lopes, Najette Amara...
146
Voted
BMCBI
2005
97views more  BMCBI 2005»
15 years 4 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
HVEI
2009
15 years 2 months ago
Ecological optics of natural materials and light fields
The appearance of objects in scenes is determined by their shape, material properties and by the light field, and, in contradistinction, the appearance of those objects provides u...
Sylvia C. Pont