Mixture models have been widely used for data clustering. However, commonly used mixture models are generally of a parametric form (e.g., mixture of Gaussian distributions or GMM),...
Flow cytometry (FC) is a powerful technology for rapid multivariate analysis and functional discrimination of cells. Current FC platforms generate large, high-dimensional datasets...
Finite mixture model is a powerful tool in many statistical learning problems. In this paper, we propose a general, structure-preserving approach to reduce its model complexity, w...
Linear Discriminant Analysis (LDA) is a popular statistical approach for dimensionality reduction. LDA captures the global geometric structure of the data by simultaneously maximi...
We present a novel probabilistic latent variable model to perform linear dimensionality reduction on data sets which contain clusters. We prove that the maximum likelihood solution...