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BMCBI
2010
118views more  BMCBI 2010»
14 years 10 months ago
svdPPCS: an effective singular value decomposition-based method for conserved and divergent co-expression gene module identifica
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
Wensheng Zhang, Andrea Edwards, Wei Fan, Dongxiao ...
BMCBI
2010
105views more  BMCBI 2010»
14 years 10 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2008
200views more  BMCBI 2008»
14 years 10 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
ALMOB
2006
110views more  ALMOB 2006»
14 years 10 months ago
New journal: Algorithms for Molecular Biology
This editorial announces Algorithms for Molecular Biology, a new online open access journal published by BioMed Central. By launching the first open access journal on algorithmic ...
Burkhard Morgenstern, Peter F. Stadler
ESWA
2008
219views more  ESWA 2008»
14 years 10 months ago
Business intelligence approach to supporting strategy-making of ISP service management
The recent deregulation of telecommunication industry by the Taiwanese government has brought about the acute competition for Internet Service Providers (ISP). Taiwan's ISP i...
Sheng-Tun Li, Li-Yen Shue, Shu-Fen Lee
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