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BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
BMCBI
2011
14 years 1 months ago
ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
Osvaldo Zagordi, Arnab Bhattacharya, Nicholas Erik...
SIGIR
2012
ACM
13 years 1 days ago
Explicit relevance models in intent-oriented information retrieval diversification
The intent-oriented search diversification methods developed in the field so far tend to build on generative views of the retrieval system to be diversified. Core algorithm compon...
Saul Vargas, Pablo Castells, David Vallet
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ACMACE
2006
ACM
15 years 3 months ago
Sketching-out virtual humans: from 2D storyboarding to immediate 3D character animation
Virtual beings are playing a remarkable role in today’s public entertainment, while ordinary users are still treated as audiences due to the lack of appropriate expertise, equip...
Chen Mao, Sheng Feng Qin, David K. Wright