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» Testing Properties of Constraint-Graphs
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BMCBI
2008
110views more  BMCBI 2008»
14 years 11 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
CANDC
2008
ACM
14 years 11 months ago
'Genome order index' should not be used for defining compositional constraints in nucleotide sequences
Background: The Z-curve is a three dimensional representation of DNA sequences proposed over a decade ago and has been extensively applied to sequence segmentation, horizontal gen...
Eran Elhaik, Dan Graur, Kresimir Josic
FOCM
2008
100views more  FOCM 2008»
14 years 11 months ago
A Unifying Local Convergence Result for Newton's Method in Riemannian Manifolds
We consider the problem of finding a singularity of a differentiable vector field X defined on a complete Riemannian manifold. We prove a unified result for the existence and local...
Felipe Alvarez, Jérôme Bolte, Julien ...
BMCBI
2006
118views more  BMCBI 2006»
14 years 11 months ago
Microarray image analysis: background estimation using quantile and morphological filters
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
Anders Bengtsson, Henrik Bengtsson
BMCBI
2006
101views more  BMCBI 2006»
14 years 11 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...