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» The Equivalence between Biology and Computation
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RECOMB
2007
Springer
16 years 1 months ago
An Efficient and Accurate Graph-Based Approach to Detect Population Substructure
Currently, large-scale projects are underway to perform whole genome disease association studies. Such studies involve the genotyping of hundreds of thousands of SNP markers. One o...
Srinath Sridhar, Satish Rao, Eran Halperin
RECOMB
2004
Springer
16 years 1 months ago
The Statistical Significance of Max-Gap Clusters
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
Rose Hoberman, David Sankoff, Dannie Durand
BMCBI
2008
104views more  BMCBI 2008»
15 years 1 months ago
InteroPORC: an automated tool to predict highly conserved protein interaction networks
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
Magali Michaut, Samuel Kerrien, Luisa Montecchi-Pa...
RECOMB
2004
Springer
16 years 1 months ago
The evolutionary capacity of protein structures
In nature, one finds large collections of different protein sequences exhibiting roughly the same three-dimensional structure, and this observation underpins the study of structur...
Leonid Meyerguz, David Kempe, Jon M. Kleinberg, Ro...
CORR
2004
Springer
144views Education» more  CORR 2004»
15 years 1 months ago
The Google Similarity Distance
Words and phrases acquire meaning from the way they are used in society, from their relative semantics to other words and phrases. For computers the equivalent of `society' is...
Rudi Cilibrasi, Paul M. B. Vitányi